Cerebral vascular lesions in diabetes mellitus: Solved and unresolved questions

Abstract

A review of the Russian and international publications on the frequency, risk factors and characteristics of ischemic stroke in patients with type 2 diabetes mellitus (DM-2) is presented. We present a detailed description of specific risk factors for DM-2 (chronic and acute hyperglycemia, recurrent hypoglycemia, insulin resistance and hyperinsulinemia). Current demands to targeted glucose control in patients who survived vascular events are presented. Attention is drawn to the high frequency of complex multiple vessel lesion in patients with DM-2.