Synthesis and anti-platelet activity of thiosulfonate derivatives containing a quinone moiety

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Abstract

Thiosulfonate derivatives based on quinones were synthesized for studying "structure-activity relationship" compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was assessed.

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Bolibrukh, K., Polovkovych, S., Khoumeri, O., Halenova, T., Nikolaeva, I., Savchuk, O., … Novikov, V. (2015). Synthesis and anti-platelet activity of thiosulfonate derivatives containing a quinone moiety. Scientia Pharmaceutica, 83(2), 221–231. https://doi.org/10.3797/scipharm.1411-14

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