Saccharin as a salt former. Enhanced solubilities of saccharinates of active pharmaceutical ingredients

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Abstract

Saccharin, acting as a weak acid, forms salts with basic APIs and these salts have the desirable property of enhanced water solubility. © The Royal Society of Chemistry 2005.

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Bhatt, P. M., Ravindra, N. V., Banerjee, R., & Desiraju, G. R. (2005). Saccharin as a salt former. Enhanced solubilities of saccharinates of active pharmaceutical ingredients. Chemical Communications, (8), 1073–1075. https://doi.org/10.1039/b416137h

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