A new ring bromination method for aromatic compounds under solvent-free conditions with NBS/Al2O3

Abstract

Alumina supported N-bromosuccinimide was found to be an efficient reagent for ring bromination of a number of aromatic compounds under solvent-free conditions. In the absence of the alumina the reactions are slow and some of the substrates are recovered unchanged. Under the reaction conditions aromatic oximes are converted into the corresponding carbonyl compounds. The method is simple, safe and rapid.