2(3H)Pyrrolone - A biologically active scaffold (A review)

Abstract

Pyrrolones are potent medicinal scaffolds and exhibit a broad spectrum of biological activities. This review throws light on the detailed synthetic approaches which have been used for the synthesis of pyrrolones. This has been followed by an in depth analysis of the pyrrolones with respect to their medicinal significance. This review may help the medicinal chemists to develop new leads possessing pyrrolone nucleus with higher efficacy.