Performance of a rapid self-test for detection of Trichomonas vaginalis in South Africa and Brazil

Abstract

Women participating in studies in Brazil (n∇695) and South Africa (n∇230) performed rapid point-of-care tests for Trichomonas vaginalis on self-collected vaginal swabs. Using PCR as the gold standard, rapid self-testing achieved high specificity (99.1%; 95% confidence interval [CI], 98.2 to 99.6%) and moderate sensitivity (76.7%; 95% CI, 61.4 to 88.2%). These tests may be considered an alternative to syndromic management in resource-poor settings.