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Microbial transformation of mestranol by Cunninghamella elegans

Chemical and Pharmaceutical Bulletin (2005) 53(8) 1011-1013
DOI: 10.1248/cpb.53.1011
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Abstract

The microbial transformation of an oral contraceptive, mestranol (1) by Cunninghamella elegans yielded two hydroxylated metabolites, 6β-hydroxymestranol (2) and 6β,12β-dihydroxymestranol (3). Metabolite 3 was found to be a new compound. These metabolites were structurally characterized on the basis of spectroscopic techniques. © 2005 Pharmaceutical Society of Japan.

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Choudhary, M. I., Musharraf, S. G., Siddiqui, Z. A., Khan, N. T., Ali, R. A., & Atta-ur-Rahman. (2005). Microbial transformation of mestranol by Cunninghamella elegans. Chemical and Pharmaceutical Bulletin, 53(8), 1011–1013. https://doi.org/10.1248/cpb.53.1011

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