Abstract
CD8+ T cells have a protective role in experimental visceral leishmaniasis. However, the observation that inflammatory cytokines induce bystander activation of CD8+ T cells questions the need for antigen-dependent effector function. Here, we demonstrate that successful adoptive immunotherapy with CD8+ T cells is strictly dependent upon the presence of cognate antigen. Copyright © 2006, American Society for Microbiology. All Rights Reserved.
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CITATION STYLE
Polley, R., Stager, S., Prickett, S., Maroof, A., Zubairi, S., Smith, D. F., & Kaye, P. M. (2006). Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen. Infection and Immunity, 74(1), 773–776. https://doi.org/10.1128/IAI.74.1.773-776.2006
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