Significance of malondialdehyde in Iraqi women patients with iron deficiency anemia

Abstract

Evidence from previous epidemiological and clinical studies suggests a possible relationship between antioxidant stress and anemia. Our study was conducted from February 2021 to May 2021 and the aim of the study is to evaluate oxidative stress by studying lipid peroxidation for women only in Najaf Governorate / Iraq with iron deficiency anemia compared to healthy controls. A case-control study was designed to evaluate malondialdehyde (MDA). The number of samples was 180, 90 of whom were IDA patients and the other 90 were normal control subjects. Serum levels of Malondialdehyde were assessed using enzyme-linked immunosorbent assay (ELISA). The results showed a stati stically significant increase in malondialdehyde (MDA) levels (8.54 ± 2.5 (nmol/ml) versus 4.39 ± 0.83 (nmol/ml); P<0.001), in addition to an increase in lipid peroxidation in women with iron deficiency anemia.