UJI AKTIVITAS ANTIJERAWAT DAN KARAKTERISTIK FISIK EMULGEL MINYAK ATSIRI DAUN JERUK PURUT (Citrus hystrix DC.) DENGAN BASIS GEL HPMC TERHADAP Propionibacterium acne

Abstract

Tests were conducted antiacne activity emulgel of essential kaffir lime leaves oils (Citrus hystrix DC.) against Propionibacterium acne. Antiacne activity assays performed by agar diffusion method at a concentration of 1%, 2%, 4%, and 8%. The results showed that of the kaffir lime leaves oil can inhibit the growth of P.acne. The greatest inhibitory regions shown the higher concentration of kaffir lime leaves oils, then the inhibitory of growth inhibition area P.acne increasingly widespread of 8% > 4% > 2% > 1%. Relationships increased concentration of essential lime leaves oils in the emulgel dosage effect on physical properties such as chemical emulgel pH, viscosity, and the power spread. From the test results it is known that the higher the concentration of oils in the preparation kaffir lime leaves emulgel the pH and viscosity of the lower F0> F1> F2> F3> F4, while increasing power spread F0 4% >2%>1%. Hubungan peningkatan konsentrasi minyak atsiri daun jeruk purut dalam sediaan emulgel berpengaruh terhadap sifat fisika kimia emulgel seperti pH, viskositas, dan daya sebar. Dari hasil uji diketahui bahwa semakin tinggi konsentrasi minyak atsiri daun jeruk purut dalam sediaan emulgel maka pH dan viskositas semakin rendah F0>F1>F2>F3>F4, sedangkan daya sebar semakin meningkat F0