Abstract
The ethyl acetate soluble fraction from the roots of Sanguisorba tenuifolia was found to have a hypoglucemic effect in alloxan-induced diabetic rats. Two new triterpenoids, identified as 2-oxo-3β,19α-dihydroxyolean-12-en- 28-oic acid β-D-gluco-pyranosyl ester (1) and 2a,19α-dihydroxy-3-oxo- 12-ursen-28-oic acid β-D-glucopyranosyl ester (4) were isolated from this fraction, along with thirteen known triterpenoids. Their structures were elucidated by chemical and spectroscopic methods. All these compounds demonstrated inhibitory activities against α-glucosidase with IC 50 values in the 0.62-3.62 mM range. © 2011 by the authors; licensee MDPI, Basel, Switzerland.
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Kuang, H. X., Li, H. W., Wang, Q. H., Yang, B. Y., Wang, Z. B., & Xia, Y. G. (2011). Triterpenoids from the roots of Sanguisorba tenuifolia var. Alba. Molecules, 16(6), 4642–4651. https://doi.org/10.3390/molecules16064642
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