Problems with Interhemispheric Transfer of Information in Complete or Partial Agenesis of the Corpus Callosum

Abstract

Objective: We assessed the presence of poor interhemispheric communication in agenesis of the corpus callosum (ACC) and hydrocephalus. Methods: With spe cially designed tests, nine children with ACC were investigated and compared with 11 controls to see the degree of impairment present. Two subjects with a stretched cor pus callosum due to hydrocephalus also were tested. A subject with the corpus callo sum divided was tested for comparison. Results: Significant differences were found in tests of coordination and stereognosis both with ACC patients and the calloso tomy subject. No impairments were found in the hydrocephalics. Conclusions: When compared with controls, ACC patients perform poorly in several tests. The calloso tomy patient also showed evidence of impairment similar to that of the ACC patients. © 2001, Sage Publications. All rights reserved.