Immunoelectron microscopy - Methods and protocols

Abstract

The tribute that the scientific community has to pay to this technique is impressive: thanks to immunoelectron microscopy the scientist’s dream to link strucure (form) and function, one of the dreams that shaped even the phylosopical reflection of our predecessors, well, this dream has became nearly a full reality while it was just fact and function, a battle between a dead body (structure) and a ghost (function). Immunoelectron microscopy provided in fact some of the first examples of our technical capacity to show how the form of a structure is so deeply linked to its functional activity. In a perspective view it has been something conceptually forerunner of present day synthetic biology and molecules design capacities to provide us with new functions or the way to modify/alter those functions we are interested in....