Treatment of leprosy

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Abstract

Multidrug therapy composed of rifampicine, sulfon and clofazimine is the only useful method for rapidly inactivating a multibacillary patient and avoiding sulfone resistance. Rifampicin should be taken by the patient under medical control. Sulfones and clofazimine can be self-administered by the patient. Monotherapy with sulfone, which is still used should give way to multidrug therapy, no matter what the conditions of treatment. We use two therapeutic treatment regimens that are efficient, practical, cheap and well tolerated by multibacillary patients. For interpolar paucibacillary patients, who wish to avoid reversal reactions that are neurologically paralysing, we administer sulfortomidicine (Fanasil) associated with rifampicin, during 6 months and continue with it during one and a half years. Up to the present moment results are excellent.

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Languillon, J. (1987). Treatment of leprosy. Revista de Leprologia (Fontilles), 16(2), 173–178. https://doi.org/10.1097/00000441-189708000-00020

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