Abstract
A nested case-control study was conducted in two trials of prophylaxis for Mycobacterium avium complex (MAC) infection to describe the specific signs, symptoms, and laboratory abnormalities of MAC disease in AIDS. Patients had ≤200/mm3 CD4 cells and a prior AIDS-defining illness. Of 571 patients, 102 (17.9%) developed MAC bacteremia during a mean follow-up of 256 days. Among cases of MAC disease, 90 were compared with 180 matched controls. Patients with MAC disease were more likely than controls to have lower weights (66.3 vs. 71.1 kg, P = .001) and Karnofsky scores (74.3 vs. 84.4, P
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CITATION STYLE
Gordin, F. M., Cohn, D. L., Sullam, P. M., Schoenfelder, J. R., Wynne, B. A., & Horsburgh, C. R. (1997). Early manifestations of disseminated Mycobacterium avium complex disease: A prospective evaluation. Journal of Infectious Diseases, 176(1), 126–132. https://doi.org/10.1086/514014
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