Optimizing Embryo Transfer Outcomes: Determinants for Improved Outcomes Using the Oocyte Donation Model

Abstract

The past decade has seen increased success rates with assisted reproductive technologies (ART), however, the overall pregnancy and implantation rates have remained relatively low. These low rates continue even though we now have improved stimulation protocols and laboratory techniques. Three areas that have gained specific attention include 1) identification of the optimal uterine environment; 2) extended embryo culture to the blastocyst stage; and 3) the embryo transfer (ET) technique, which has historically been viewed as an unimportant variable in the success of an ART treatment cycle..