From pathway to products: Canadian achievements in plant specialized metabolism

Abstract

Canada has made significant contributions to the field of plant biochemistry, with numerous researchers actively focusing on elucidating the biosynthetic pathways of plant specialized metabolites and producing these compounds in heterologous systems, such as bacteria, yeast, or other plant species. The review aims to highlight the strengths of Canadian research in this domain over the last three decades. It will describe advances in pathway elucidation, enzyme characterization, and production of enzymes and metabolites in heterologous systems, particularly in the areas of alkaloids, terpenoids, and phenolic compounds. Canadian researchers have not only made pivotal scientific discoveries but have also ensured the continuity of scientific excellence by mentoring new generations of principal investigators in plant specialized metabolites. These advances warrant recognition and financial support to retain future talent and to maintain Canada’s leadership in scientific progress on the global stage.