AEPEI scoring system to predict mortality among patients diagnosed with infective endocarditis after surgery at the philippine heart center: a retrospective analytical cross-sectional study

Abstract

Background: Infective endocarditis (IE) is a life-threatening disease which continues to pose significant challenges in clinical practice. Surgery for IE while curative can be associated with considerable morbidity and mortality. We sought to determine the utility of a French based risk score in determining outcomes of patients with IE undergoing surgery. Methodology: This was a retrospective analytical cross-sectional study. Patients admitted and diagnosed with definite Infective endocarditis based on the modified Duke's criteria at our Heart Center who underwent surgical treatment. Clinical and echocardiographic characteristics were described and the sensitivity and specificity of the AEPEI score was analyzed. Results: Sixty six patients were included in the study and underwent surgical intervention. The most common type of endocarditis involves the native valve (90.9%, n = 60). Multivalvular involvement was also noted in 12 patients (18.1%). Acute kidney injury and pneumonia were the most common major adverse events of patients. The post-surgery in-hospital mortality rate was 10.6%. The sensitivity and specificity of AEPEI is 100% and 50% in predicting in hospital mortality Conclusion: In patients with IE undergoing surgery, mortality rate in our institution is lower compared to previous data. Our results suggest that the AEPEI is a useful tool to predict in hospital mortality to help in prognostication as well as clinical and surgical decision making (Figure Presented).