Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. 1. Taxonomy, isolation, physico-chemical properties and biological activities

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Abstract

New antibiotics designated decatromicins A and B were isolated from the culture broth of Actinomadura sp. MK73-NF4. They were purified by butyl acetate extraction, silica gel column chromatography, silica gel TLC and Sephadex LH-20 column chromatography. Decatromicins A and B inhibited growth of Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).

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Momose, I., Iinuma, H., Kinoshita, N., Momose, Y., Kunimoto, S., Hamada, M., & Takeuchi, T. (1999). Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. 1. Taxonomy, isolation, physico-chemical properties and biological activities. Journal of Antibiotics, 52(9), 781–786. https://doi.org/10.7164/antibiotics.52.781

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