Infiltration pattern predicts metastasis and progression better than the T-stage and grade in pancreatic neuroendocrine tumors: a proposal for a novel infiltration-based morphologic grading

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Abstract

The advancing edge profile is a powerful determinant of tumor behavior in many organs. In this study, a grading system assessing the tumor-host interface was developed and tested in 181 pancreatic neuroendocrine tumors (PanNETs), 63 of which were

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Taskin, O. C., Reid, M. D., Bagci, P., Balci, S., Armutlu, A., Demirtas, D., … Adsay, V. (2022). Infiltration pattern predicts metastasis and progression better than the T-stage and grade in pancreatic neuroendocrine tumors: a proposal for a novel infiltration-based morphologic grading. Modern Pathology, 35(6), 777–785. https://doi.org/10.1038/s41379-021-00995-4

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