Evaluation of the cobas TaqMan MTB test for the detection of mycobacterium tuberculosis complex according to acid-fast-bacillus smear grades in respiratory specimens

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Abstract

We evaluated the performance of the Cobas TaqMan MTB test (Roche Diagnostics, Basel, Switzerland), stratified by acid-fast bacilli (AFB) smear grades. The sensitivity of this test in smear-positive specimens was > 95% in all grades, while that in trace and negative specimens was 85.3% and 34.4%, respectively.

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Huh, H. J., Koh, W. J., Song, D. J., Ki, C. S., & Lee, N. Y. (2015). Evaluation of the cobas TaqMan MTB test for the detection of mycobacterium tuberculosis complex according to acid-fast-bacillus smear grades in respiratory specimens. Journal of Clinical Microbiology, 53(2), 696–698. https://doi.org/10.1128/JCM.02630-14

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