Syntheses and biological activities of 1,4-iminoalditol derivatives as α-L-fucosidase inhibitors

Abstract

A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of α-l-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented. © Schweizerische Chemische Gesellschaft.