Effect of purple passion fruit extract cream (Passiflora edulis sims var. edulis) 6% against striae distensae

Abstract

BACKGROUND: Striae distensae is a skin disorder that causes cosmetic and psychological problems. Purple passion fruit (Passiflora edulis Sims var. Edulis) is widely cultivated, especially in North Sumatra. The seeds are abundant and unused industrial waste. Purple passion fruit seeds contain piceatannol, ascorbic acid, flavonoids, resveratrol, hydroalcohols, and sterols which play a role in the repair of striae distensae through anti-inflammatory mechanisms, increase fibroblast proliferation and collagen production, increase crosslinking between collagen fibers and moisturizers. AIM: To determine the effect of 6% purple passion fruit (P. edulis Sims var. Edulis) seed extract cream on striae distensae. PATIENTS AND METHODS: This study is a pre-experimental clinical trial with a pretest-posttest research design on 40 patients with striae distensae. The diagnosis was confirmed by history and clinical evaluation using the Manchester scar scale before and after administration of 6% purple passion fruit extract cream at baseline, 2, 4, 6, and 8 weeks. Adverse effects were recorded during the study and satisfaction levels were assessed at the end. RESULTS: The majority of subjects’ ages ranged from 29 to 39 years (72.5%). There was a significant reduction in Manchester scar scale in striae distensae, both after being given a 6% purple passion fruit extract cream or a combination of 1% tretinoin cream for 8 weeks, with a mean reduction of 25% (p = 0.000). Striae distensae after being given 6% purple passion fruit extract cream compared to 6% purple passion fruit extract cream combined with 1% tretinoin cream, there was no significant difference (p = 0.791). From a total of 40 patients, none experienced side effects (0%). As many as 57.5% of the subjects showed a good level of satisfaction. CONCLUSION: The use of 6% purple passion fruit seed extract cream can improve the appearance of striae distensae without side effects and the level of satisfaction is good.