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The Hippo-YAP/TAZ pathway mediates geranylgeranylation signaling in breast cancer progression

Molecular and Cellular Oncology (2016) 3(3)
DOI: 10.4161/23723548.2014.969638
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Abstract

Protein geranylgeranylation (GGylation) regulates the function of various signal transducers including small GTPases and Ggamma subunits. The role of GGylation in breast cancer progression is poorly understood. Recent studies suggest that GGylation promotes the proliferation and migration of breast carcinoma cells through the Hippo-YAP/TAZ pathway.

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Lin, Q., & Yang, W. (2016). The Hippo-YAP/TAZ pathway mediates geranylgeranylation signaling in breast cancer progression. Molecular and Cellular Oncology, 3(3). https://doi.org/10.4161/23723548.2014.969638

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