Granulomatous slack skin

Abstract

A case of granulomatous slack skin (GSS) is reported. A 56-year-old male patient presented with widespread papules and nodules for 25 years, with slack skin and pendulous folds for 10 years. Physical examination showed more than three handred of papules or nodules all over the body, with a predilection towards the axillary, inguinal and cervical areas. No infiltrated plaques were found. Histopathological examination revealed predominant lymphocyte infiltration in the dermis, with numerous multinucleated giant cells and loss of elastic fibers. Immunohistochemistry showed positive stain for CD3, CD68, CD45RO; and negative stain for CD20, CD79a. The diagnosis was established as granulomatous slack skin.