Antimicrobial behavior of nanocoated orthodontic micro-implants: An in vitro study

Abstract

OBJECTIVE: The need to overcome the failure of orthodontic micro-implants which might reach to 30% has led to the development of different methods, one of which is nanoparticle deposition. AIM OF STUDY: To evaluate the anti-microbial efficiency of TiO2 and ZnO nanoparticles (NP) when used as a coating for orthodontic micro-implants. METHODS: Thirty titanium alloy micro-implants were used in the presented study. They were divided into three groups according to the coating method and the coating materials used: The control group without surface coating; the titanium dioxide (TiO2)-coated group, in which direct current (DC) spattering was used to coat the micro-implants with a TiO2 layer; and the TiO2 and zinc oxide (TiO2ZnO)-coated group, in which the micro-implants were coated with a TiO2 layer via direct current (DC) spattering and a zinc oxide (ZnO) layer via laser vacuum. The micro-implant surfaces were characterized using scanning electron microscopy (SEM) and an energy-dispersive spectrometer (EDS). The antibacterial susceptibility was assessed using gram-positive and gram-negative bacteria. RESULTS: SEM and EDS tests confirmed the coating of the micro-implants in the TiO2-and TiO2ZnO-coated groups. The micro-implants in the TiO2-and TiO2ZnO-coated groups demonstrated higher antibacterial ability than the control group. CONCLUSION: This study demonstrated the significance of improving the surface of orthodontic micro-implants by coating them with TiO2 and ZnO nanoparticles to improve osseointegration and prevent biofilm formation.