186. MORTALITY PATTERN IN RHEUMATIC DISEASES: DATA FROM A TERTIARY CARE HOSPITAL IN NORTHERN INDIA

Abstract

Introduction: Accurate understanding of mortality pattern is important for public health point of view as well as for clinical management of rheumatic diseases. Objectives: To study the mortality of rheumatic diseases in a tertiary hospital. Material and Methods: Death register from Jan 2004 to Dec 2014 was analyzed for the data. Results: In 10 years, a total of 430 343 admissions to SKIMS were recorded, during which 19 391 (4.51%) patients died. We found 133 cases of rheumatic diseases which constituted 0.7% of total deaths during this period. Majority (83.3%) of the patients with rheumatic disease were in the age group of 20-70 years with almost similar distribution in different subgroups. The mean age at death in patients with non rheumatic disease (n = 19 258) was 48.03 ± 23.38 years (range 1 day - 110 years) compared to 43.94 ± 17.79 years (range 11- 85 years) in patients with Rheumatic disease (P = 0.044). In rheumatic disease group majority (75.2%) were females while males constituted only 24.8% of the deaths. There were 41 (30.8%) SLE, 37 (27.8%) RA, 18 (13.5%) Vacuities, 12 (9.02%) MCTD, 9 (6.8%) APLA, 8 (6%) Systemic sclerosis, 4 (3%) Sjogren's syndrome, 2 (1.5%) Polymyositis patients and 2 (1.5%) patients had a combination of SLE and rheumatoid arthritis (Rhupus). Sepsis, cardiovascular diseases, and organ failure (respiratory and renal) were the main causes of death in patients with rheumatic diseases. Conclusion: Patients Rheumatic diseases have premature mortality compared to the non Rheumatic patients and sepsis being the leading cause of death.