Abstract
Violations of the process of methylation reveal itself at the early stages of malignant transformation of cells, and the content of 5-methylcytosine can serve as a diagnostic test for tumor formation and treatment of disease. The carried out studies revealed the correlation of antitumor activity of MM-therapy (the use of coherent millimeter electromagnetic waves of low intensity for therapy) with inhibition of methylation of tumor DNA in vivo. It is revealed in our experiments that an half-hour exposure of MM-radiation results in the tumor growth inhibition by 33.5% and a sharp suppression of the level of DNA-methylation 2.5 times. The results obtained in this experiment indicate the prospects of working out the MM-therapy for clinical oncology in the treatment of malignant neoplasms.
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CITATION STYLE
Kalantaryan, V., Martirosyan, R., Nersesyan, L., Aharonyan, A., Danielyan, I., Stepanyan, H., … Khudaverdyan, N. (2011). Effect on tumoral cells of low intensity electromagnetic waves. Progress In Electromagnetics Research Letters, 20, 97–105. https://doi.org/10.2528/PIERL10110806
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