Stem cells carrier scaffolds for tissue engineering

Abstract

Mesenchymal Stem Cells (MSCs) can be isolated from several body tissues, including dental tissues. As a result of being capable of differentiating into a variety of cell types, it can be presumed that stem cell therapy has an advantage compared to other tissue repair methods. Objective: The aim of this paper is to provide a review about current and future materials for scaffolds to carry stem cells in tissue engineering in Dentistry, especially for bone tissue repair. Literature review: MSCs have great therapeutic potential in tissue engineering, they can be expanded in vitro, and combined with scaffolds to be inserted into defects to promote healing and tissue replacement. Conclusion: Stem cells from dental tissues have a real potential in Advanced Therapies. The combination of inductive scaffold materials with stem cells might optimize the approaches for bone regeneration. Although there are numerous available biomaterials potentially compatible to combine with MSCs, more studies need to be performed, due to the fact that for each indication there will be a more suitable material according to the defect’s biological and mechanical requirement.