Bovine adenovirus serotype 7 infections in postweaning calves

Abstract

Objective-To detect bovine adenovirus serotype 7 (BAV-7) infections in calves by use of viral isolation and serologic testing. Animals-205 postweaning calves. Procedure-121 calves were assembled by an order buyer through auction markets in eastern Tennessee and transported to New Mexico where they were commingled with 84 healthy ranch-reared calves. Tests included viral isolation in cell culture from peripheral blood leukocytes (PBL) and detection of serum BAV-7 antibodies by use of microtitration viral neutralization. Results- BAV-7 was isolated from PBL of 8 calves and seroconversion to BAV-7 was detected for 38 of 199 (19.1%) calves. Concurrent bovine viral diarrhea virus infections were detected in most calves from which BAV-7 was isolated. Conclusions and Clinical Relevance-Results of our study indicate that BAV-7 infections can be found in postweaning commingled calves and may develop more commonly in calves with concurrent infections with viruses such as bovine viral diarrhea virus (BVDV).