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Synthesis and SAR studies of praziquantel derivatives with activity against Schistosoma japonicum

Molecules (2013) 18(8) 9163-9178
DOI: 10.3390/molecules18089163
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Abstract

The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as leads for further optimization. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

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Wang, W. L., Song, L. J., Chen, X., Yin, X. R., Fan, W. H., Wang, G. P., … Feng, B. (2013). Synthesis and SAR studies of praziquantel derivatives with activity against Schistosoma japonicum. Molecules, 18(8), 9163–9178. https://doi.org/10.3390/molecules18089163

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