Undifferentiated embryonal sarcoma of the liver (UESL) represents a heterogeneous group of tumors derived from mesenchymal tissues. Earlier cytogenetic studies in limited cases demonstrated that UESL is associated with a recurrent translocation t(11;19)(q11;q13.3-q13.4) or add(19)(q13.4). In this report, we present our array comparative genomic hybridization (aCGH), fluorescence in situ hybridization (FISH) findings, and a missense mutation of TP53 gene by DNA sequencing in a 19-year-old patient with UESL. The data were compared to laboratory findings reported by previous studies. © 2012 Hu et al.; licensee BioMed Central Ltd.
CITATION STYLE
Hu, X., Chen, H., Jin, M., Wang, X., Lee, J., Xu, W., … Niu, J. (2012). Molecular cytogenetic characterization of undifferentiated embryonal sarcoma of the liver: A case report and literature review. Molecular Cytogenetics. https://doi.org/10.1186/1755-8166-5-26
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