Acid esters of triterpenoids and steroid glycosides from Gambeya africana

Abstract

Chemical studies of the CH2Cl2-MeOH extract of the seeds of Gambeya africana (Baker) Pierre led to the isolation of 15 compounds. Their structures were established on the basis of spectroscopic methods and chemical reactions. They comprised five new fatty acid esters of erythrodiol, [3β-octacosanoyloxy-12-oleanen-28-ol, 3β-triacontanoyloxy-12-oleanen-28-ol, 3β-dotriacontanoyloxy-12-oleanen-28-ol, 3β-tetratriacontanoyloxy-12-oleanen-28-ol and 3β-hexatriacontanoyloxy-12-oleanen-28-ol], one new steroidal glycoside, [3β-O-β-xylopyranosylchondrillasterol] and nine known compounds, (3β-octadecanoyloxy-12-oleanene, 3β-eicosanoyloxy-12-oleanene, 3β-docosanoyloxy-12-oleanene, 3β-acetoxy-12-oleanene, erythrodiol, 28-hydroxy-β-amyrone, chondrillasterol, chondrillasterone and 3β-O-β-glucopyranosylchondrillasterol).