Cannabis. V1). Cannabigerolic Acid Monomethyl Ether and Cannabinolic Acid

Abstract

The original cannabinoids including Δ2-tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabichromenic acid (CBCA), and a new component, cannabigerolic acid monomethyl ether (CBGAM) were isolated with simple column chromatographic technique from the fresh Cannabis of the domestic strain. Cannabinolic acid (CBNA), observed in the stored Cannabis, was synthesized from THCA by means of ultraviolet (UV) light irradiation, and artificial conditions to yield CBN A from THCA, comparing with Δ3-isomer were investigated. © 1970, The Pharmaceutical Society of Japan. All rights reserved.