Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru

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Abstract

In vivo antimalarial drug efficacy studies of uncomplicated Plasmodiumfalciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.

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Magill, A. J., Zegarra, J., Garcia, C., Marquiño, W., & Ruebush, T. K. (2004). Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru. Revista Da Sociedade Brasileira de Medicina Tropical, 37(3), 279–281. https://doi.org/10.1590/S0037-86822004000300015

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