Go with the flow: Simplified MRD in LMIC ALL

Abstract

In this issue of Blood, Pedrosa et al1 provide long-term results of a pilot study in children with precursor B-cell ALL conducted in a Brazilian center in a limited-resource setting. This pilot study incorporated a previously described simplified flow cytometric methodology for minimal residual disease (MRD) assessment in B-lineage ALL adapted for use in limited-resource settings to assess response at days 19 and 26.2,3