Geometric Deep Learning for Post-Menstrual Age Prediction Based on the Neonatal White Matter Cortical Surface

Abstract

Accurate estimation of the age in neonates is useful for measuring neurodevelopmental, medical, and growth outcomes. In this paper, we propose a novel approach to predict the post-menstrual age (PA) at scan, using techniques from geometric deep learning, based on the neonatal white matter cortical surface. We utilize and compare multiple specialized neural network architectures that predict the age using different geometric representations of the cortical surface; we compare MeshCNN, Pointnet++, GraphCNN, and a volumetric benchmark. The dataset is part of the Developing Human Connectome Project (dHCP), and is a cohort of healthy and premature neonates. We evaluate our approach on 650 subjects (727 scans) with PA ranging from 27 to 45 weeks. Our results show accurate prediction of the estimated PA, with mean error less than one week.