Peptides. VI. Some Oxime Carbonates as Novel t -Butoxycarbonylating Reagents

Abstract

Several t-butoxycarbonyl derivatives of oximes were prepared through the corresponding oxime chloroformates. Of these, diethyl (t-butoxycarbonyloxyimino)malonate and 2-(t-butoxycarbonyloxyimino)-2-phenylacetonitrile were utilized for the preparation of t-butoxycarbonylamino acids under various conditions. The results are summarized in a table.