Tick-borne encephalitis with hemorrhagic syndrome, Novosibirsk Region, Russia, 1999

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Abstract

Eight fatal cases of tick-borne encephalitis with an unusual hemorrhagic syndrome were identified in 1999 in the Novosibirsk Region, Russia. To study these strains, we sequenced cDNA fragments of protein E gene from six archival formalin-fixed brain samples. Phylogenetic analysis showed tick-borne encephalitis variants clustered with a Far Eastern subtype (homology 94.7%) but not with the Siberian subtype (82%).

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Ternovoi, V. A., Kurzhukov, G. P., Sokolov, Y. V., Ivanov, G. Y., Ivanisenko, V. A., Loktev, A. V., … Loktev, V. B. (2003). Tick-borne encephalitis with hemorrhagic syndrome, Novosibirsk Region, Russia, 1999. Emerging Infectious Diseases, 9(6), 743–746. https://doi.org/10.3201/eid0906.030007

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