Mortality difference from Klebsiella aerogenes vs Enterobacter cloacae bloodstream infections

Abstract

Members of the order Enterobacterales, including Escherichia coli, Klebsiella species and Enterobacter species, are important patho-gens in healthcare-associated infections. Higher mortality has been reported from infections due to Klebsiella pneumoniae than from E. coli, but prior studies comparing Enterobacter aerogenes (recently renamed Klebsiella aerogenes) bacteraemia and Entero-bacter cloacae complex bacteraemia have yielded conflicting results regarding whether clinical outcomes differ. We found bacte-raemia with K. aerogenes was independently associated with greater risk of 30-day mortality than bacteraemia with Enterobacter cloacae complex.