The Effect of Bifidobacterium Administration in Patients with Leukemia

Abstract

The intestinal flora of patients with leukemia was changed by chemotherapy. In many cases, Klebsiella, Citrobacter, and Proteus vulgaris, etc., which are normally sparse, increased greatly. Anaerobic bacteria, especially Bacteroides, also increased. Many cases of Candida overgrowth were also observed. This imbalance of intestinal microorganisms was counteracted by oral Bifidobacterium administration. Endotoxin in the blood and indican in the urine were tested in leukemia patients. These tests were positive in many cases and were reduced by Bifidobacterium administration.