Efficacy of intravenous iron sucrose therapy in iron deficiency Anaemia of pregnancy

Abstract

Objectives: To determine the efficacy of intravenous iron sucrose, in anemic pregnant women, presenting at Jinnah Hospital, Lahore. Study design: Descriptive case series Place & duration of study: Study was carried out in department of Obstetrics and Gynaecology, Jinnah Hospital, Lahore over a period of six months from 23-10-2008 to 22-04-2009. Patients and methods: 130 cases with proved iron deficiency anemia having haemoglobin between 8-10g% were included in this study. total iron deficit was calculated by standard formula. target haemoglobin was 11g%. iron sucrose was administered by intravenous infusion. haemoglobin was repeated 3 weeks after the last dose of intravenous iron sucrose. Results: Most of the patients 78 (60%) had gestational age 31-34 weeks, 39 patients (30.0%) had 29-30 weeks gestational age while 13 patients (10.0%) were between 26-28 weeks gestation. Mean gestational age was observed 32.4±2.7. Distribution of cases by economic status showed, 52 patients (40.0%) belonged to lower class, 48 patients (37.0%) belonged to middle class and 30 patients (23.0%) were of upper class. Therapy was effective in 98 patients (75.3%). There were no allergic reactions. Conclusion: this study showed a significant improvement in the haemoglobin of the patients after receiving iron sucrose infusion. patients achieved the target of 11 gram %. it is safe and well tolerated.