Studies in Subjects with Long-Term Nonprogressive Human Immunodeficiency Virus Infection

Abstract

In a small percentage of persons infected with human immunodeficiency virus type 1 (HIV-1), there is no progression of disease and CD4+ T-cell counts remain stable for many years. Studies of the histopathological, virologic, and immunologic characteristics of these persons may provide insight into the pathogenic mechanisms that lead to HIV disease and the protective mechanisms that prevent progression to overt disease. © 1995, Massachusetts Medical Society. All rights reserved.