Abstract
Nephrotoxicity is a serious disadvantage of cyclosporin A and may lead to irreversible loss of renal function.1 Recent evidence suggests that it may be a haemodynamic phenomenon due to intrarenal vasoconstriction.23 Studies in animals show that the calcium channel blocker nifedipine may reverse the effects of long term treatment with cyclosporin.4 We report the influence of nifedipine on graft function in a retrospective study of renal transplant recipients given cyclosporin. © 1987, British Medical Journal Publishing Group. All rights reserved.
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CITATION STYLE
Feehally, J., Walls, J., Mistry, N., Horsburgh, T., Taylor, J., Veitch, P. S., & Bell, P. R. F. (1987). Does nifedipine ameliorate cyclosporin A nephrotoxicity? British Medical Journal (Clinical Research Ed.), 295(6593), 310. https://doi.org/10.1136/bmj.295.6593.310
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