An Infrequent Histopathological Diagnosis in a Prevalent Systemic Disease: A Case of Renal Sarcoidosis

Abstract

Sarcoidosis is a multisystemic granulomatous disease that results from an aberrant immunological response to certain antigens. Although pulmonary involvement predominates, renal involvement may also occur. We present the case of a 59-year-old woman with a recent diagnosis of hepatic sarcoidosis and a history of non-compliance with treatment who was admitted to the hospital for study of acute kidney injury. Renal dysfunction was assumed to be a result of acute interstitial nephritis, as revealed on renal biopsy, and alterations in glomerular hemodynamics due to hypercalcemia. Renal function recovered and serum calcium levels normalized with the introduction of corticosteroid therapy.