Epidemiologic studies of Reye's syndrome: Cases seen in Pittsburgh, October 1973 - April 1975

Abstract

Twenty seven cases of Reye's syndrome (RS) were admitted over a 19 month period to one urban hospital. All lived in a suburban or rural location and 23 cases occurred during two influenza outbreaks. Two to three months following the last cases of RS, 24 families of RS cases and 21 control families representing neighbors or friends were interviewed for factors which could predispose to RS. Children with RS had an illness immediately preceding the onset of RS more frequently than did controls (p