FR-111142 is a new angiogenesis inhibitor produced by a fungus Scolecobasidium arenarium F-2015. FR-111142 inhibited endothelial cell proliferation in vitro and angiogenesis in the growing chick chorioallantoic membrane model in vivo. Further, FR-111142 also suppressed the solid tumor growth in mice. © 1992, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
CITATION STYLE
Otsuka, T., Shibata, T., Tsurumi, Y., Takase, S., Okuhara, M., Terano, H., … Imanaka, H. (1992). A New Angiogenesis Inhibitor, Fr-111142. Journal of Antibiotics, 45(3), 348–354. https://doi.org/10.7164/antibiotics.45.348
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