Journal ArticleOPEN ACCESS

Nucleolar disruption leads to the spatial separation of key 18S rRNA processing factors

  • Turner A
  • Knox A
  • Watkins N
RNA Biology (2012) 9(2) 175-186
DOI: 10.4161/rna.18811
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Abstract

Many chemotherapeutic drugs cause the downregulation of ribosome production and the disruption of nucleolar function. This stabilizes p53 and leads to either cell cycle arrest or apoptosis. It is n...

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Turner, A. J., Knox, A. A., & Watkins, N. J. (2012). Nucleolar disruption leads to the spatial separation of key 18S rRNA processing factors. RNA Biology, 9(2), 175–186. https://doi.org/10.4161/rna.18811

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