Journal Article

Synthesis of podophyllotoxin and its derivatives via nicl2/nabh4 reduction of isoxazoline ring

Asian Journal of Chemistry (2013) 25(17) 9555-9557
DOI: 10.14233/ajchem.2013.15073
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Abstract

A novel synthesis of podophyllotoxin was carried out in four steps. The key step was reduction of isoxazoline ring followed by diazotization and the resultant alkene was treated with Mn(OAc)3/CH3COOK to form podophyllotoxin.

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Babu, M. S., & Rai, K. M. L. (2013). Synthesis of podophyllotoxin and its derivatives via nicl2/nabh4 reduction of isoxazoline ring. Asian Journal of Chemistry, 25(17), 9555–9557. https://doi.org/10.14233/ajchem.2013.15073

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