Drug susceptibility of recent isolates of Nocardia seriolae from cultured fish

Abstract

A study was undertaken to profile antibiotic sensitivity of Nocardia seriolae isolated from diseased fish cultured in Ehime and Kochi Prefectures from 1999 to 2001. In vitro antibacterial activities of 10 chemotherapeutic agents against N. seriolae isolates were determined as minimum inhibitory concentrations (MICs). All the 60 isolates examined showed susceptibility to kanamycin. Resistance to oxolinic acid and fosfomycin was found in all the isolates and some of the isolates showed resistance to erythromycin, spiramycin and kitasamycin. Multi-drug resistance patterns were also recorded in some of the isolates.